I am not affiliated with this brand and it is not sold on Amazon -Destiny

The difference between the Nuna Pipa AIRE Rx and the Nuna Pipa Rx: 

• The Pipa AIRE Rx is one of the lightest infant car seats available (5.7lbs without base opposed to the Nuna Pipa Rx (7.7lbs without the base)
• The Pipa AIRE Rx has better ventilation 
• The Pipa Rx has a heavier base
• The Pipa AIRE Rx has a bigger canopy for sun protection

Both have great safety features and use quality materials. 

Materials

• Infant head and body inserts are made of Merino wool and TENCEL™*** lyocell fiber blend that is soft, naturally controls moisture, and is environmentally friendly
• Exposed aerospace aluminum handle adds a contemporary aesthetic and enhances the seat's intuitive functionality
• Super-resilient top-of-the-line plastics for a heavy-duty secure shell

- From fabric to foam and beyond each element is smartly sourced to be both flame-resistant and contain no added fire-retardant chemicals making it safer for baby

- GREENGUARD Gold Certified to meet some of the world's most rigorous third-party chemical emissions standards, and certified to not contribute to indoor air pollution or chemical exposure

- Additional GOTS organic cotton infant insert and harness cover set

Benefits:

• FAA certified for aircraft use with or without a base
• Connects with all Nuna strollers to create a stylish travel system*
• 5-second steel-reinforced True lock™ installation makes set up swift, simple, and safe**
• Side Impact Protection (SIP) for ultimate baby safekeeping
• Open belt path with lock off secures lap and shoulder belt
• Features Aeroflex™ foam that is cleverly lightweight, resilient, and minimizes force transferred to baby
• The deep seat design creates a cocoon-like space, ensuring a better fit and comfortable car seat for your baby.
• 3-position height-adjustable headrest and 5-point harness keeps little ones in place
• Removable infant head and body inserts nestle baby in comfort and security
• Tailor tech™ memory foam seat panel and headrest provides a comfortable custom fit
• UPF 50+ canopy with 2 positions and a flip-out eyeshade protects from sun exposure
• The iconic Sky drape™ provides baby with ultimate privacy for quiet moments
• Soft yet durable micro-knit fabric for refined style and casual warmth
  
• Luxe leatherette carry handle for more secure gripping

Nuna: 

⭐️ Nuna was founded in 2007 in the Netherlands. Since then, it has become a globally recognized brand, especially in North America and Europe

⭐️ Nuna has a strong reputation for customer satisfaction, offering excellent customer service and a solid warranty on their products

Nuna products are designed in the Netherlands, but the manufacturing of most of their products takes place in China