SenP2 Protease (sentrin-specific protease 2) is a highly active recombinant enzyme that catalyzes the deconjugation of SUMO1, SUMO2, and SUMO3 peptides from targeted proteins, making it an essential tool for SUMO-tag removal and functional protein expression studies.

Key Features & Specifications:

• Source & Expression Host: Escherichia coli (E. coli)
• Expressed Region: Asp363-Leu589 (UniProt: Q9HC62-1)
• Tagging: His-tag (N-terminus) for easy downstream removal or detection
• Purity: >90% as determined by Coomassie staining
• Formulation: Supplied in 20 mM Tris-HCl, pH 7.5, 100 mM NaCl, 5 mM 2-mercaptoethanol, and 50% glycerol
• Molecular Weight: ~29 kDa

Applications:

• Highly efficient cleavage of SUMO-fusion proteins
• Deubiquitinating and deSUMOylating activity assays
• Post-translational modification (PTM) analysis

Catalog #: SNP2-301

Application Disclaimer: For Research Use Only (RUO). This product is for research use only and is not intended for diagnostic or therapeutic use in humans or animals.