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home > TelN Protelomerase, Recombinant | Amid Biosciences > TelN Protelomerase, Recombinant | Amid Biosciences
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TelN Protelomerase, Recombinant | Amid BiosciencesTelN Protelomerase from E. coli bacteriophage N15processes circular and linear plasmid DNA containing the target sitetelRLto produce linear double stranded DNA with covalently closed ends. The 56 bptelRLtarget site consists of a centraltelO palindrome of 22 bp and two 14 bp flanking sequences comprising inverted repeats.telOis separated from these repeats by 3 bp on each side. ThetelRLsequence is sufficient for TelN mediated processing. TelN has
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TelN Protelomerase from E. coli bacteriophage N15Êprocesses circular and linear plasmid DNA containing the target siteÊtelRLÊto produce linear double-stranded DNA with covalently closed ends. The 56-bpÊtelRLÊtarget site consists of a centralÊtelOÊ palindrome of 22 bp and two 14-bp flanking sequences comprising inverted repeats.ÊtelOÊis separated from these repeats by 3 bp on each side. TheÊtelRLÊsequence is sufficient for TelN-mediated processing. TelN has cutting-ligating enzyme activity and covalently ligates at the cleavage site forming hairpin termini.

TelN Protelomerase, Recombinant | Amid Biosciences

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